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mail.msu.edu listens on both ports. Port 465 is SSL encrypted only. Port 25 uses TLS to switch to encryption. I have found no consistent behavior from clients explaining when they need one or the other. Your own configuration, for example, uses port 25 then, with no apparent reason, needs port 465. (this is with Eudora?) A wild guess for you is that for 4 weeks you were sending mail to users @msu.edu which does not require authentication and encryption. At week 4 you sent to a non-msu.edu address and relay was denied. Another wild guess is that there is some auto-patch from MS that causes things to work differently. -- Ed Symanzik MSU Mail Team [log in to unmask]