Microsoft does have some recommendations on the size of the Exchange
database that you may want to keep in mind:
"Microsoft recommends that information store databases grow no larger than
50 GB. Assuming proper maintenance, there are no operational issues with
running mailbox stores larger than 50 GB; however, backup and restore times
may make larger mailbox stores unsuitable for some service level agreements
(SLAs)."
The article that I found with this information can be found at
http://technet.microsoft.com/en-us/library/aa995715.aspx
Ashley
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