SCIENCE AT THE EDGE, INTERDISCIPLINARY PHYSICS

Fri, 18 Mar 2016, 11:30 am - 12:30 pm

1400 BPS Bldg.

Mark Goulian

Department of Biology and Department of Physics & Astronomy, University of Pennsylvania

 Bacterial Signal Transduction: an E. coli View of the World

Abstract:

All cells sense and respond to physical and chemical cues in their environments. They accomplish this through signal transduction systems—networks of interacting proteins that detect and interpret specific input signals and control appropriate cellular responses. In bacteria, one of the major modes of signal transduction is mediated by a class of circuits that are composed of two components: a sensory protein and a response regulator. These two-component systems have been found in remarkable numbers within individual organisms and across different bacterial species. They play a central role in regulating basic aspects of microbial physiology and mediate responses to diverse environmental signals.  I will describe recent work in which we have explored the organization and properties of these circuits in the particularly well studied and genetically tractable organism Escherichia coli.  

Refreshments at 11:15 am.

Shawna Prater / Secretary

Astrophysics Group

Michigan State University

567 Wilson Road, Room 3261

Biomedical Physical Sciences Bldg

East Lansing, MI 48824-2320

Ph: (517) 884-5601 Fax (517) 432-8802

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