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I will attend the seminar. Dr. Pramanik, Computer Science and Engineering. > Dr. Rafael Casellas is the Science at the Edge seminar speaker on Friday, > October 18. His abstract is below and attached to this message. Dr. > Kefei Yu is hosting the speaker If you would like to meet with Dr. > Casellas, please reply to this message with your available times > (flexibility is helpful in scheduling the appointments) and I will get > back with you to confirm the time. > > Friday, October 18 > 7:45-9:00 Open - Breakfast w/speaker (he is staying at Kellogg > Center and charge meal to his room) > 9:00-9:45 Open > 9:45-10:30 Filled > 10:30-11:15 Filled > 11:15-11:30 Speaker Preparation, 1425 BPS > 11:30-12:30 Seminar, 1425 BPS > 12:30-2:00 Filled - Lunch w/speaker > 2:00-2:45 Filled > 2:45-3:30 Filled > 3:30-4:15 Open > 4:15 Dr. Yu takes Dr. Casellas to the airport > Rafael Casellas > Genomics & Immunity, NIAMS > > NIH, Bethesda, MD > > The NIH Mouse Regulome Project > > > The National Institutes of Health recently launched the NIH Mouse Regulome > Project (NMRP), an initiative that seeks to characterize all > gene-regulatory elements and ranscription factor binding sites in the > mouse genome. This is achieved by mapping genome-wide DNA methylation, > chromatin modifications that demarcate promoters and enhancers, PolII > binding, transcriptome analyses, and DNAseI hypersensitivity. In contrast > to the previous human ENCODE project, which assigned enhancers to cognate > promoters based on proximity, the NMRP makes use of a newly developed > deep-sequencing technique (ChIA-PET) that precisely maps promoter-enhancer > interactions with unprecedented detail. To complement these efforts, a > Genome Editing facility was created to assemble hundreds of zinc finger > nucleases with the goal of deleting regulatory domains and study their > activity in vivo. The seminar will highlight the applications of these > technologies to mouse ES cells and B lymphocytes. > > > Helen Geiger > Administrative Assistant > Quantitative Biology Graduate Program and > Gene Expression in Development and Disease > 212 Biochemistry Building > Michigan State University > East Lansing, MI 48824 > Email: [log in to unmask]<mailto:[log in to unmask]> > Phone: 517-432-9895 > QB Website: http://www.qbi.msu.edu/ > GEDD Website: http://www.gedd.msu.edu/ > > <10-18-13CasellasAbstractFlyer.doc> > > Katheryn Meek, Professor > Microbiology & Molecular Genetics, Pathobiology & Diagnostic Investigation > Biomedical and Physical Sciences Building > 567 Wilson Rd., Rm 2215 > Michigan State University > East Lansing, MI 48824 > > [log in to unmask]<mailto:[log in to unmask]> > > > > > >