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EDGE SEMINAR QB/GEDD Friday, March 29 at 11:30am Room 1400 Biomedical and Physical Sciences Bldg. Refreshments at 11:15 Matthew Rockman Department of Biology and Center for Genomics & Systems biology New York University Genetic Consequences of Mating-system Evolution in C. elegans C. elegans, the workhorse model organism for studies of development and behavior, reproduces primarily by self-fertilization in hermaphrodites. Its recent ancestors, however, were obligate outcrossers, with separate sexes. The transition from outcrossing to selfing altered the selective regime in which these animals live, and it simultaneously transformed the genetic structure of the species. I'll show how mating-system evolution in C. elegans has affected the distribution of genetic and phenotypic variation in this species, focusing on two genetic case studies: early embryogenesis and mating behavior. Helen Geiger, Administrative Assistant Quantitative Biology Graduate Program and Gene Expression in Development and Disease Biochemistry 603 Wilson Road, Room 212 East Lansing, MI 48824 Email: [log in to unmask] Phone: 517-432-9895 QB Website: http://www.qbi.msu.edu/ GEDD Website: http://www.gedd.msu.edu/