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PHYSICS AND ASTRONOMY

Science at the Edge

 

Friday, February 12, 2010

 

11:30a

 

1400 Biomedical & Physical Sciences Bldg

Refreshments at 11:15a in 1400 BPS Bldg

 

Sunney Xie

Harvard University

 

“Life at the Single Molecule Level”

 

In a living cell, gene expression – the transcription of DNA to messenger RNA followed by translation to protein – occurs stochastically, as a consequence of the low copy number of DNA and mRNA molecules involved.  Can one monitor these processes in a living cell in real time?  How do cells with identical genes exhibit different phenotypes?  Recent advances in single-molecule imaging in living bacterial cells allow these questions to be answered at the molecular level in a quantitative manner.  It was found that rare events of single molecules can have important biological consequences.

 

 

Kim Crosslan

Undergraduate Secretary

Dept. Physics & Astronomy

Michigan State University

1312 Biomedical & Physical Sciences

East Lansing,  MI  48824

517-884-5531

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