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There is a 64-bit version of ESET NOD32 as I downloaded the trial of it yesterday afternoon. from Eset's website: System Requirements Processors supported: Intel or AMD x86/x64 Operating Systems: Microsoft Windows 2000 Professional, Microsoft Windows XP (32- and 64-bit editions), Microsoft Windows Vista (32- and 64-bit editions), Microsoft Windows Server 2000, Microsoft Windows Server 2003 (32- and 64-bit editions), Microsoft Windows Server 2008 (32- and 64-bit editions) Memory: 44 MB Disk Space (download): 28 MB Disk Space (installation): 35 MB" Stephen Bogdanski Network Support College of Veterinary Medicine Michigan State University >>> "Esther V. V. Reed" <[log in to unmask]> 5/15/2009 9:34 AM >>> What are you using for antivirus protection (AV) on your 64-bit MS Windows Server 2008 non-Exchange boxes? ESET and Windows Defender do not have 64-bit versions available. Symantec and Kaspersky say they do, but I have read that the apps are really 32-bit so you get a performance hit. The only one I've found so far that is supposed to be a native 64-bit app is Outpost. Have you used Outpost? What do you think of it? Do you know of any other native 64-bit AV products for WinSvr 2008? ~ Esther Esther V. V. Reed IT Systems Administrator MSU Graduate School