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Friday, September 6 - Interdisciplinary Physics Seminar 11:30 a.m., Room 1400 BPS Bldg Speaker: Ilya Nemenman Affiliation: Department of Physics, Department of Biology, and Computational and Life Sciences Initiative, Emory University Abstract: Signal or information processing and shaping of a response (a.k.a, signal transduction, regulation, sensing) is a common function performed by organisms on all levels of organization. In this talk, we will study information processing in cellular systems to answer questions like: Does the fidelity of information processing matter evolutionarily? What are the fundamental physical limits to the fidelity of information processing set by the intrinsic fluctuations in the cellular biochemical machinery? How close the cells come to these limits? What can they do to improve the performance? After introducing the general theoretical framework, we will address these and related questions in the specific experimental context of mammalian NF-kB signaling. Shawna Prater / Secretary Astrophysics Group Michigan State University 567 Wilson Road, Room 3261 Biomedical Physical Sciences Bldg East Lansing, MI 48824-2320 Ph: (517) 884-5601 Fax (517) 432-8802 [log in to unmask]<mailto:[log in to unmask]>, [log in to unmask]<mailto:[log in to unmask]>