SCIENCE AT THE EDGE SEMINAR

QB/GEDD

Friday, September 9 at 11:30am

Room 1400 Biomedical and Physical Sciences Bldg.

Refreshments at 11:15

Haixu Tang

Department of Informatics and Computing, Indiana University

 

 

 

 

Next Generation Software Tools for

Next Generation Sequence Analysis

 

 

The rapid advance of the massively parallel sequencing (often referred to as the Next Generation Sequencing, NGS) technologies has revolutionized DNA sequencing by reducing both its throughtput and cost by several magnitudes in the past few years. As a result, DNA sequencing has become available for not only large genome centers, but also individual biological labs, a trend called the democratized genomics. With the fast-growing applications of NGS on a wide spectrum of biological problems, ranging from gene expression analysis (i.e. RNA-seq) to metagenomics, pressures are mounting on the bioinformatics community to come up with software systems to analyze such data. In this talk, I will present a few case studies to address the computational challenges to design and implement these sequence analysis systems, with focuses on the requirements of Simplicity, Scalability, Speed and Security of the systems.

 

 

Helen Geiger

Administrative Assistant

Quantitative Biology Graduate Program and

Gene Expression in Development and Disease

502B Biochemistry Building

Michigan State University

East Lansing, MI   48824

Email: [log in to unmask]

QB Website: http://www.qbi.msu.edu/

GEDD Website: http://www.gedd.msu.edu/