> Michigan State University
>
>  
>
> Science at the Edge
>
> Engineering Seminar
>
>  
>
> *Friday, December 5, 2008*
>
> 11:30 a.m., Room1400 Biomedical and Physical Sciences Building
>
> Refreshments served at 11:15 a.m.
>
>  
>
> *Stanislav Y. Shvartsman*
>
> Department of Chemical Engineering and Lewis Sigler Institute for 
> Integrative Genomice
>
> Princeton University
>
> * *
>
> *Cell Signaling in Equations and Embryos*
>
> * *
>
> Animal development relies on a handful of signaling pathways, which were 
> discovered by genetic and biochemical techniques. Exploring the dynamics 
> and function of these pathways is essentially impossible without 
> mathematical models. We are combining imaging, computational, and 
> genetic approaches in order to develop and experimentally test 
> mathematical models of the Mitogen Activated Protein Kinase (MAPK) 
> pathway, a key regulator of tissues in animals from worms to humans.  
> Using the terminal patterning system in the early Drosophila embryo as 
> an experimental model, we are examining how multiple levels of 
> organization within the MAPK pathway control its dynamics and function. 
> We discovered that the gradient of MAPK phosphorylation is established 
> by a cascade of diffusion-trapping modules and are now studying how this 
> gradient controls its biochemical and transcriptional targets.
>
>  
>
> For further information please contact Prof. Christina Chan, Department 
> of Chemical Engineering and Materials Science at [log in to unmask]
>
> Persons with disabilities have the right to request and receive 
> reasonable accommodation. Please call the Department of Chemical 
> Engineering and Materials Science at 355-5135 at least one day prior to 
> the seminar; requests received after this date will be met when possible.
>
>
>